Charmme was only 13 years old when she acted in her first film, Nee Thodu Kaavali (released march 2002). This film was a big flop, but helped Charmme get noticed by the south Indian film industry. Her next film was Kadal Azhavatillai (Tamil) which was a hit. After that she acted in a couple more Tamil films but they bombed at the box office.
Her re-entry to Telugu movies happened with Sri Anjaneyam, directed by ace director Krishna Vamsi. This too was a failed attempt. It was followed by another failure with Chanti, paired against Ravi Teja. She finally got a big break in Telugu with Gowri in which she paired with Sumanth. She didn't have to look back afterwards. The stupendous success of Mass with Nagarjuna strengthened her position in Tollywood.
Charmme's most notable and critically acclaimed film so far is Anukokunda Oka Roju. It was a heroine-oriented thriller and had her playing the lead in it. Her performance in the movie was acclaimed by critics.
Her recent film, Pournami, was a flop, but her performance was appreciated. Though she did not learn south Indian classical dances, her Bharata Natyam and Kuchipudi dances in the film were appreciated by audiences.
Charmme's latest film Chinnodu is declared a safe-player at the box-office. Her next filmRakhi (with NTR), is declared a HIT and charmme's role is appreciated. Another film, Mantra, a thriller with Charmme in the lead role, is currently in pre-production.
Three of Charmme's films, Style, Lakshmi, and Chukkallo Chandrudu, released in a period of 3 days. However, only Lakshmi and Style became hits. She was approached to do the item song in Stalin, but declined it as she was committed to other films. The chance later went on to Anushka Shetty. She also spells her first name as 'Charmme'.